Abstract: By mimicking the physiological structure and movement principles of earthworms, a bionic peristaltic drilling tool was developed to enhance the transfer efficiency of weight on bit (WOB) in long horizontal sections of horizontal wells. The tool used a pulse generator to drive multiple vibration subs, which enabled the drill string to perform peristaltic motion while reducing hydraulic pressure loss. Laboratory tests show that at a flow rate of 30 L/s, the tool’s pressure fluctuation amplitude reaches nearly 2 MPa, with a vibration frequency of 6.5 Hz, and the displacement amplitude of the three vibration subs exceeds 5 mm. The field test is conducted in the horizontal section of Well JHW83−31 in Xinjiang Oilfield, with drilling footage of 815 m and an average rate of penetration (ROP) of 12.48 m/h achieved. Compared with adjacent wells adopting drag reduction and speed increase tools such as oscillating screws and hydraulic oscillators, the average ROP increases by 15.5%. The field test results indicate that the bionic peristaltic drilling tool can alleviate the problem of drill string friction, promote the transfer efficiency of WOB, and offer an effective solution for improving the drilling efficiency of long horizontal sections in horizontal wells.