Abstract: In order to resolve a series of problems such as low water injection efficiency and short longevity that faced in the development period of water injection for cavernous fractured karst carbonate reservoirs in Tahe Oilfield, a quantitative water injection technology was studied and applied on the basis of material balance equations. The theoretical basis, technical method and application effect of quantitative water injection development technology have been analyzed and expounded in three aspects, including the quantification of water injection timing, water injection parameters in single well and unit water injection parameters. The quantitative water injection technology can avoid the problems caused by qualitative water injection in the early development process, and it has been applied in 142 wells, with a cumulative oil increment of 10.95×10⁴ t, and the water injection efficiency higher than 84.3%. The results showed that the quantitative water injection technology had a great effect in the development of cavernous fractured karst carbonate reservoirs in the Tahe Oilfield, with good value of promotion and application as a best practice for similar reservoirs.