Abstract: Liner hangers with embedded slips are structurally complex, and the slip clamping force is the key factor for successful setting the liner hangers. Based on the structures and manufacturing process of embedded slip setting systems, a mechanic model of setting system for embedded slip liner hangers was built by using matrix theories, the theoretical calculation methods were worked out for clamping force of slips, the relationship among the slip clamping force, liner weights, cutter rotation angle and friction coefficient on contact surface were analyzed. Setting tests were performed for the embedded slip liner hanger and casing, outside strain of casing was collected and analyzed with different axial loads by means of strain testing systems, the contact stress between the casing inner wall and the slip was calculated by using Lame’s Equation. Research results showed that the calculated value of contact strain between the slip and casing coincided with measured mean value. Maximum and minimum stresses are 150% and 75% of the average value respectively. The analysis and test results of setting the mechanical models can provide an important basis for structural design and the optimization of liner hangers.